Fertility preservation in pediatric female cancer patients.
OBJECTIVE: To describe and demonstrate ovarian tissue cryopreservation (OTC) as an emerging fertility preservation technique DESIGN: Video presentation. SETTING: University hospital. PATIENT(S): A 6 year-old female patient diagnosed with aplastic anemia with plan for bone marrow transplantation underwent laparoscopic unilateral oophorectomy in conjunction with surgical procedure for port placement by the pediatric surgeon, followed by […]
Ovarian manipulation in ART: going beyond physiological standards to provide best clinical outcomes
Throughout much of recent medical history, illness and treatment have been considered in terms of a profoundly simple model in which physiological knowledge should be applied and either medical treatment or surgical repair performed when a vital organ begins to lose some function. When reproductive organs begin to function abnormally, in vitro fertilization (IVF) has […]
Cellular memory of DNA damage in oocyte quality control
Females are born with a finite number of eggs that are steadily depleted throughout their lifetime. This reserve of eggs is selected from a much larger pool of millions of precursor cells, or oocytes, that form during fetal life. So there is a substantial amount of quality control during the process of forming an egg […]
Association of culture medium with growth, weight and cardiovascular development of IVF children at the age of 9 years
STUDY QUESTION: Is embryo culture media used during an IVF/ICSI treatment associated with differences in growth, body composition and cardiovascular development as determined in 9-year-old singleton IVF children? SUMMARY ANSWER: The choice of in vitro culture medium for human embryos is associated with differences in body weight, BMI, truncal adiposity, waist circumference and waist/hip ratio […]
Does a poor-quality embryo have an adverse impact on a good-quality embryo when transferred together?
This retrospective study was approved by the Ethics Committee of the Third Affiliated Hospital of Zhengzhou University. All patients who underwent in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) at the reproduction centre of the Third Affiliated Hospital of Zhengzhou University between January 2012 and December 2015 were included in this study. Patients who […]
For women undergoing IVF, is fresh or frozen embryo transfer best?
The world’s first baby born via in-vitro fertilization turned 40 years old this summer. Still, after four decades, IVF is a relatively new field with ongoing debate on how to get the best results for families who have placed their hopes—and often their personal savings—into fertility treatment. IVF experts disagree about whether transferring a fresh […]
Best practice in the diagnosis and treatment of varicocele in children and adolescents
Overview A varicocele is defined as an abnormal dilation and tortuosity of the pampiniform plexus venous system that drains the testis. The prevalence of varicocele in the adolescent population has been shown to mirror that of adults. A recent European study that included over 7000 patients found a 15.7% varicocele rate in young males with […]
Novel distance‑progesterone‑combined selection approach improves human sperm quality
Human sperm are subject to natural selection by a number of processes, including chemotaxis and the challenge of the long distance swim from the vagina to the fallopian ampulla in the human female reproductive system. Sperm chemotaxis is the term given to the movement of sperm in the direction of a factor (peptide or chemical) […]
Does a nut-rich diet lead to better sperm quality?
Sperm count is on the decline in Western societies, according to recent studies, which means that men’s reproductive health is suffering. How can it be improved? A healthful diet that is abounding in nuts might help, researchers suggest. In 2017, a large meta-analysis focusing on men’s reproductive health in Western countries found that sperm concentration, […]
Animating embryos: thein totorepresentationof life
In the preface to the tenth and latest edition of his authoritative textbook on developmental biology, Scott F. Gilbert states that the science of becoming is currently itself undergoing a ‘metamorphic molt’, at the end of which there will be an as ‘yet unnamed developmental science’. 1 To a large extent, systems biology is responsible […]
