Cell and genetic predictors of human blastocyst hatching success in assisted reproduction

The aim was to identify cell and genetic predictors of human blastocyst hatching success in assisted reproduction programmes via a prospective case-control study. Blastocysts, donated by couples in assisted reproduction programmes were used. Hatching success assessment was performed after 144-146 h post-fertilization. The mRNA expression levels of cathepsin V (CTSV), GATA-binding protein 3 (GATA3) and […]

I Simpósio Nacional de Embriologistas SBRH

O I Simpósio Nacional de Embriologistas SBRH foi um sucesso e marcou o início de um novo tempo nos eventos de embriologia. Um público ativo, formado por grandes embriologistas, novos embriologistas, estudantes e amigos fizeram desse evento um momento especial! Siga nossas Redes Sociais: Facebook: @embriologiasbrh @faceSBRH

Taking paracetamol during pregnancy may reduce fertility of daughters

Taking paracetamol during pregnancy may impair the future fertility of female offspring, according to a review published in Endocrine Connections. The article reviews three separate rodent studies that all report altered development in the reproductive systems of female offspring from mothers given paracetamol during pregnancy, which may impair their fertility in adulthood. Paracetamol, or acetaminophen, […]

I Simpósio Nacional de Embriologistas da SBRH foi um sucesso

O I Simpósio Nacional de Embriologistas da SBRH aconteceu no dia 28/04 em Florianópolis e foi um sucesso! Temas atuais, relevantes e que fazem parte do dia a dia do embriologista foram abordados e discutidos por profissionais de destaque no cenário da Reprodução Assistida contemporânea. O evento teve um ambiente descontraído, com uma combinação de […]

Fertility breakthrough: New research could extend egg health with age

Princeton University researchers led by Coleen Murphy have identified a key protein in old, poor-quality C. elegans oocytes (unfertilized eggs): cathepsin B. When they administered a cathepsin B inhibitor midway through the fertile window — on day 3 of the worms’ adulthood, the equivalent of a woman in her early 30s — they successfully extended […]

Low total testosterone in men widespread, linked to chronic disease

A male’s total testosterone level may be linked to more than just sexual health and muscle mass preservation, a new study finds. Low amounts of the hormone could also be associated with chronic disease, even among men 40 years of age and younger. “If we look at data for men from a population level, it […]

Like babies, eggs send signals when ‘hungry’

A growing oocyte in the middle, which is very large with a bright green rim, surrounded by many small red follicle cells whose nuclei are stained blue. The thin bright-green hair-like structures between them are the feeding tubes, which grow out from the follicle cells when they receive signals from the oocyte. This image was […]

Genetic profiling could improve IVF success

Genetic profiling could help determine whether an embryo created through in-vitro fertilisation (IVF) is likely to successfully transfer to the womb, increasing the success rate of the procedure. It’s part of a field of work looking at the role of genetics in fertility. “Understanding why some people do not have children, and developing treatments for […]

Monkey see, monkey 2: Scientists clone monkeys using technique that created Dolly the sheep

(CNN)For the first time, scientists say they created cloned primates using the same complicated cloning technique that made Dolly the sheep in 1996. Shanghai scientists created two genetically identical and adorable long-tailed macaques. The monkeys are named Hua Hua and Zhong Zhong, a version of the Chinese adjective Zhonghua which means the “Chinese nation” or […]

Transfer of Fresh versus Frozen Embryos in Ovulatory Women

In vitro fertilization (IVF) has evolved rapidly since its inception 40 years ago. Advancements include controlled ovarian stimulation with gonadotropin, which multiplied the number of oocytes retrieved, and embryo yopreservation, which made it possible to conserve surplus embryos for further use, thus increasing cumulative live-birth rates after an IVF cycle. Observational studies1,2 and small randomized, […]